A hardened New Orleans cop, Dave Robicheaux, finally tosses in the badge and settles into life on the bayou with his wife. But a bizarre plane crash draws him back into the fray when his family is viciously threatened.

UNIT-即联合情报特遣部队，在联合国主持下运作的独立情报组织。在隐藏于深海之中的古老生物浮出水面之后，UNIT以及目前的掌门人凯特·莱斯布里奇·斯图尔特必须阻止这群曾经称霸古地球的远古生物卷土重来引发全球性危机。同时在陆地与浪潮的黑暗深处，SeaSalt和Barclay之间的结盟也将在这场史无前例的霸主之战中得到挑战。该剧为《神秘博士》于2005年重启后推出的第四部衍生剧。